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张其威教授

发布时间:2023-12-01 发布单位:病原微生物研究院




地址:广东省广州市天河区黄埔大道西601号暨南大学梁仲景楼七楼

邮编:510632

邮箱:zhangqw@jnu.edu.cn

招聘微生物学、分子生物学、流行病学、兽医学、药学等研究方向的硕士生、博士生、博士后、青年人才若干名,有意者请随时邮件咨询。  

  

一、个人经历

1. 学习经历

香港大学 李嘉诚医学院,博士后

武汉大学 生命科学学院,博士

武汉大学 生命科学学院, 本科

2. 工作经历

(1)暨南大学,教授/博导,副院长

(2)哈佛大学 医学院,访问学者

(3)南方医科大学 公共卫生学院,病原生物学 教授

 二、个人简介

      暨南大学生命科学技术学院教授/博导,副院长;香港大学医学院微生物系博士后,哈佛大学医学院访问学者,主要研究方向包括腺病毒流行病学、分子进化、腺病毒疫苗等。国际学术刊物上发表多篇研究论文,论文引用7000多次(ESI高被引论文5篇); 参编Elsevier出版社《Molecular Medical Microbiology》英文版; 获Springer Nature 2023年度最佳论文奖(STTT)。目前担任中华预防医学会疫苗与免疫分会委员,中国疫苗行业协会疫苗学教育专委会委员和疫苗基础研究专委会委员;担任第13届国际腺病毒大会分会主持人,首届和第二届全国腺病毒学术研讨会大会共同主席,第四届全国病毒学青年学者学术研讨会大会共同主席。在教学方面,指导学生参加国家大学生创新创业训练项目、 广东省“攀登计划”大学生科技创新项目、“挑战杯”大学生科技竞赛、广东省大学生预防医学实验技能大赛,获评暨南大学优秀研究生导师。本科生课程《众论生命科学》,研究生《生物学前沿》《生物医药产业创新》主讲教师。  

  

三、学术服务 

期刊论文审稿:Lancet Infectious Diseases, Signal Transduct Target Ther, Cell Discovery, Med, Emerging Infectious Diseases, mBio, Antimicrobial Agents and Chemotherapy, Cladistics, Microbiology Spectrum, Antiviral Research, Antiviral Therapy, Vaccine, Virulence, Virus Evolution, Virus Research, Viruses, Viral ImmunologyHuman Vaccines & Immunotherapeutics, Clinical Epidemiology, International Journal of Biological Sciences, Journal of Medical Virology, Journal of Visualized Experiments, Cell & Bioscience,  Frontiers in Molecular Biosciences, Virologica Sinica, Microbiology and Immunology, Scientific Reports,  Jornal de Pediatria, BMC Infectious Diseases, BMC Res Notes, Process Biochemistry, BMJ OPEN, Immunity, Inflammation and Disease, 中华实验和临床病毒学杂志, 病毒学报,中国科学, etc.

四、主要学术论文

Junxian Ou, Wendong Lan, Xiaowei Wu, Tie Zhao, Biyan Duan, Peipei Yang, Yi Ren, Lulu Quan, Wei Zhao, Donald Seto, James Chodosh, Zhen Luo, Jianguo Wu*, and Qiwei Zhang*Tracking SARS-CoV-2 Omicron diverse spike gene mutations identifies multiple inter-variant recombination events. Signal Transduction and Targeted Therapy 2022 April 26; 7(1): 138.  (医学一区,Top期刊IF: 38.104, ESI高被引论文,年度最佳论文) 

Junxian Ou, Zhonghua Zhou, Ruixue Dai, Jing Zhang, Shan Zhao, Xiaowei Wu, Wendong Lan, Yi Ren, Lilian Cui, Qiaoshuai Lan, Lu Lu, Donald Seto, James Chodosh, Jianguo Wu, Gong Zhang*, Qiwei Zhang*. V367F mutation in SARS-CoV-2 spike RBD emerging during the early transmission phase enhances viral infectivity through increased human ACE2 receptor binding affinity. Journal of Virology, 2021, 95(16):e0061721. Doi:10.1128/JVI.00617-21. Top期刊,ESI高被引论文

Junxian Ou, Jianguo Wu and Qiwei Zhang*. Structural insights into the Omicron spike trimer: tackling the challenges of continuously evolving SARS-CoV-2 variants. Signal Transduction and Targeted Therapy.  2022, 7(1): 322. Signal Transduction and Targeted Therapy 2022 April 26; 7(1): 138. (医学一区,Top期刊IF: 38.104) 

Mingfu Tian, Weiyong Liu, Xiang Li, Peiyi Zhao, Muhammad Adnan Shereen, Chengliang Zhu, Shanyu Huang, Siyu Liu, Xiao Yu, Miaomiao Yue, Pan Pan, Wenbiao Wang, Yongkui Li, Xulin Chen, Kailang Wu, Zhen Luo*, Qiwei Zhang* and Jianguo Wu*. HIF-1alpha promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19. Signal Transduct Target Ther. 2021, 6(1): 308. (医学一区,Top期刊IF: 38.104) 

 Z. Luo, Y. Liang, M. Tian, Z. Ruan, R. Su, M. A. Shereen, J. Yin, K. Wu, J. Guo, Q. Zhang*, Y. Li* and J. Wu*. Inhibition of PIKFYVE kinase interferes ESCRT pathway to suppress RNA virus replication. J Med Virol.  2023, 95(2): e28527.

Z. Lei, L. Zhu, P. Pan, Z. Ruan, Y. Gu, X. Xia, S. Wang, W. Ge, Y. Yao, F. Luo, H. Xiao, J. Guo, Q. Ding, Z. Yin, Y. Li, Z. Luo, Q. Zhang*, X. Chen* and J. Wu*. A vaccine delivery system promotes strong immune responses against SARS-CoV-2 variants. J Med Virol.  2023, 95(2): e28475. (IF 20.693)

Jing Zhao#, Shan Zhao#, Junxian Ou, Jing Zhang, Wendong Lan, Wenyi Guan, Xiaowei Wu, Yuqian Yan, Wei Zhao, Jianguo Wu, James Chodosh and Qiwei Zhang*. COVID-19: Coronavirus Vaccine Development Updates. Frontiers in Immunology.  2020, 11(3435): 602256. Top期刊引用200多次)

Zhonghua Zhou, Ziyi Yang, Junxian Ou, Hong Zhang, Qiwei Zhang*, Ming Dong* and Gong Zhang*. Temperature Dependence of the SARS-CoV-2 affinity to human ACE2 determines COVID-19 progression and clinical outcome. Computational and Structural Biotechnology Journal.  202119:161-167.(生物学二区)     

Qiwei Zhang*, Shuping Jing, Zetao Cheng, Zhiwu Yu, Shoaleh Dehghan, Amirhossein Shamsaddini, Yuqian Yan, Min Li, and Donald Seto*. Comparative Genomic Analysis of Two Emergent Human Adenovirus Type 14 Respiratory Pathogen Isolates in China Reveals Similar yet Divergent Genomes. Emerging Microbes & Infections, 2017, 6, e93. (Top期刊)  

Qiwei Zhang*, Seto D, Zhao S, Zhu L, Zhao W, Wan C*. Genome Sequence of the First Human Adenovirus Type 14 Isolated in China.  Journal of Virology, 2012, 86(12): 7019-7020Top期刊 

Qiwei Zhang*, Donald Seto, Bin Cao, Suhui Zhao, and Chengsong Wan*. Genome Sequence of Human Adenovirus Type 55, a Re-Emergent Acute Respiratory Disease Pathogen in China.  Journal of Virology, 201286(22)12441-12442Top期刊 

Pin Wan, Simeng Zhang, Zhihui Ruan, Xueli Liu, Ge Yang, Yaling Jia, Yongkui Li, Pan Pan, Wenbiao Wang, Geng Li, Xulin Chen, Zhixin Liu, Qiwei Zhang*, Zhen Luo* and Jianguo Wu*. AP-1 signaling pathway promotes pro-IL-1beta transcription to facilitate NLRP3 inflammasome activation upon influenza A virus infection. Virulence.  2022, 13(1): 502-513.  (Top期刊) 

Qiwei Zhang, Su X, Seto D, Zheng B-j, Tian X, Sheng H, Li H, Wang Y, Zhou R*. Construction and characterization of a replication-competent human adenovirus type 3-based vector as a live-vaccine candidate and a viral delivery vector.  Vaccine, 2009, 27(8): 1145-1153.  (Top期刊) 

Qiwei Zhang, Su X, Gong S, Zeng Q, Zhu B, Wu Z, Peng T, Zhang C, Zhou R. Comparative genomic analysis of two strains of human adenovirus type 3 isolated from children with acute respiratory infection in southern China.  Journal of General Virology 2006, 87(6): 1531-1541. 

Qiwei Zhang*, Shoaleh Dehghan, Donald Seto. Pitfalls of restriction enzyme analysis in identifying, characterizing, typing, and naming viral pathogens in the era of whole genome data, as illustrated by HAdV type 55. Virologica Sinica, 2016, 31(5):448-453. 

Guiyuan Han, Hongling Niu, Suhui Zhao, Bing Zhu, Changbing, Wang, Yungang Liu, Mingjie Zhang, Shu Yang, Feitong Liu, Chengsong Wan, Qiwei Zhang*. Identification and typing of respiratory adenoviruses in Guangzhou, Southern China using a rapid and simple method. Virologica Sinica, 2013, 28(2):103-108.